ugaas Ali
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oil will help somalis everywhere. even the ones in the diasporas.
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Telomerase and the Possibility of Cellular Immortality The discovery of the Hayflick limit represented a radical change in the way science looked at cellular reproduction. Before the doctor's discovery, cells were thought to be capable of immortality. Although the phenomenon of the Hayflick limit has been studied only in vitro, it eventually came to generally be accepted in the scientific community as fact. For decades, it looked like the limit was insurmountable, and it still appears that way. In 1978, however, the discovery of a segment of non-replicating DNA in cells called telomeres shed light on the possibility of cellular immortality. Telomeres are repetitive strings of DNA found at the ends of chromosome pairs within diploid cells. These strings are usually compared to the plastic ends of shoelaces (called aglets) that keep the laces from fraying. Telomeres provide the same protection to chromosomes, but the telomere on the end of each chromosome pair is shortened with each cellular division. Eventually, the telomere is depleted, and apoptosis begins. The discovery of telomeres supported the Hayflick limit; after all, it was the physical mechanism by which cells entered senescence. Just under a decade later, however, another breakthrough in cellular aging was uncovered. Telomerase is a protein that's found in all cells, but in normal cells, it's turned off -- it doesn't do anything. In abnormal cells like tumors and germ cells, however, telomerase is quite active: It contains an RNA template capable of producing new telomeres on the ends of chromosomes in aging cells. Telomerase has the aging research community excited for two reasons. First, since it's naturally active in tumors and can be detected in urine samples, testing for the presence of telomerase can lead to more effective testing of cancer patients. Second, researchers have figured out how to extract telomerase and synthesize it. Potentially, if active telomerase is added to normal adult cells, they'll continue to replicate long beyond their Hayflick limit. In one study that supports this notion, researchers reported that cells to which they'd introduced telomerase had replicated 20 more times than their normal life span would indicate -- and were still dividing [source: Cherfas]. Science has yet to definitively prove that telomerase can produce cellular immortality. There seems to be myriad factors involved in programmed cellular death beyond the destruction of telomeres. As long as humans fear death, though, there will always be research into overcoming these natural obstacles to our immortality, cellular or otherwise.
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Why do cells commit suicide? When Dr. Leonard Hayflick performed his experiments using human cells grown in a culture, he managed to pull back the curtain on an ancient process that essentially prevents immortality. The process of cellular death exists within our genetic code. The nucleus of a diploid cell (a cell with two sets of chromosomes) is comprised of DNA information contributed by each of an organism's parents. Since the key to the Hayflick limit is found in the cell's nucleus, we are basically programmed to die. Why is this? There are several reasons why a cell should be programmed to die after a certain point. In the developmental stages, for example, human fetuses have tissue that creates some webbing between our fingers. As we gestate, this tissue undergoes apoptosis that ultimately allows our fingers to form. Menstruation -- the monthly process of shedding the lining of the uterus -- is also carried out through apoptosis. Programmed cellular death also combats cancer (defined as uncontrolled cellular growth); a cell that turns cancerous still has a life span like any other cell and will die out eventually. The drugs used in chemotherapy are meant to accelerate this process by triggering apoptosis in cancerous cells. Apoptosis is the result of several signals from both inside and outside a cell. When a cell stops receiving the hormones and proteins it needs to function or sustains enough damage to stop functioning properly, the process of apoptosis is triggered. The nucleus explodes and releases chemicals that act as signals. These chemicals attract phospholipids that engulf the cell fragments, degrade the individual chromosomes and carry them out of the body as waste. Clearly, apoptosis is an intensely regulated and highly refined process. How, then, could we ever possibly thwart it? Let's find out on the next page.
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In a small laboratory in Philadelphia, Penn., in 1965, a curious young biologist conducted an experiment that would revolutionize the way we think about aging and death. The scientist who conducted that experiment, Dr. Leonard Hayflick, would later lend his name to the phenomenon he discovered, the Hayflick limit. Dr. Hayflick noticed that cells grown in cultures reproduce by dividing. They produce facsimiles of themselves (by a process known as mitosis) a finite number of times before the process stops for good and the cell dies. In addition, cells frozen during their lifetimes and later returned to an active state had a kind of cellular memory: The frozen cells picked up right where they left off. In other words, interrupting the cells' life span did nothing to lengthen it. Hayflick found that cells go through three phases. The first is rapid, healthy cell division. In the second phase, mitosis slows. In the third stage, senescence, cells stop dividing entirely. They remain alive for a time after they stop dividing, but sometime after cellular division ends, cells do a particularly disturbing thing: Essentially, they commit suicide. Once a cell reaches the end of its life span, it undergoes a programmed cellular death called apoptosis. When a new cell is born from an older one through cell division, it begins its own life span. This span appears to be governed by DNA, located in the nucleus of a cell. A student of Hayflick's later found that when he removed the nucleus of an old cell and replaced it with the nucleus of a young cell, the old cell took on a new life. The old cell's life span took on that of a young cell. Like any other cell (except for stem cells), it divided most rapidly early in its lifetime, eventually slowing cellular division as it aged, before stopping altogether and undergoing apoptosis. The implications of the Hayflick limit are staggering: Organisms have a molecular clock that's inexorably winding down from the moment we're born. We'll explore that idea further on the next page.
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maybe science can explain what religious scholars from all faith failed to define or explain for thousands of years. when asked next time to explain faith, say it's in your gene.
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Whether or not you are religious and believe in God is down to your genes, says Dean Hamer, National Cancer Institute's Gene Structure Regulation Unit, USA. He reckons Jesus, Mohammed (the prophet) and Buddha probably carried the 'God Gene' in them. Church representatives have criticised Dean Hamer's findings. Church representatives say Hamer fails to understand exactly what faith is and what it entails. This is not the first time Hamer has come out with controversial findings. In 1993, he said there was a DNA sequence associated with homosexuality. Hamer claims there is a version of the VMAT2 gene that is a 'God Gene'. The presence of this version of the gene makes the person who has it more religious and spiritual than people who do not. Hamer has written a book called 'The God Gene - How Faith is Hard Wired into our Genes'. Hamer studied 2,000 DNA samples. He interviewed 2,000 people extensively (226 questions in each interview). The questions, among other things, looked at how spiritual a person is and what their level of faith in God is. He found that the VMAT2 Gene was significantly more common among people who believed in a higher spiritual being. According to his research, whether or not your upbringing is religious has no bearing on how religious you turn out to be - but the presence of the VMAT2 Gene version does. Hamer believes Buddha, Mohammed and Jesus probably had the version of the VMAT2 Gene. He said they all experienced a series of mystical experiences or alterations in consciousness. Hamer said "This means that the tendency to be spiritual is part of genetic make-up. This is not a thing that is strictly handed down from parents to children. It could skip a generation - it's like intelligence." A spokesman for the Church of Scotland, Donald Bruce, said Hamer's declarations were nothing more than a publicity stunt as his book is launched. He said God makes himself available to all equally and there is no such thing as a God Gene. According to Donald Bruce, Hamer had told him a year ago that the term 'God Gene' was misleading. This is not the first time the Church has disagreed with the findings of scientists. Many years ago, the Church got upset with Galileo because he said the earth went round the sun, he also said the earth was round (not flat).
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funny article and i thoroughly enjoyed it. before the extreme religious nutcases trash my thread please keep in mind nobody gives a damn about your opinion and for the godless freaks for the love of heaven enjoy the article. no one cares for your questions and beliefs. cheers.
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God, the author of The Last Testament: A Memoir, took some time off from helping Tim Tebow and Jeremy Lin to thank the scientists for helping him find that particle that he’s been missing for years—who would’ve thought to look in the particle collider! First off, they’re all My particles, OK? I made every last one of them, from the hunky handsome proton to the waifish, Starbucks-named neutrino. So when you attach My name only to the Higgs boson you insult the decillions of quarks, leptons, gluons, and all the other “little particles” without whose hard work and collaborative spirit the universe would cease to exist, at least with the same brio. Secondly, congratulations! You did a heck of a job. First and foremost, kudos to Professor Higgs himself, the man who decades ago predicted the existence of a mass-bestowing particle. As you may know he is an avowed atheist, so I thought it was rather kind of Me to let him revel in his earthly success before sending him off to spend eternity as the anguished m in a fiery E=mc2 conversion sequence. In truth I’m not that surprised you guys found it—sorry, “guys and girls.” Old Testament habits die hard! Humanity has always had a talent for having dogged faith in, then interpreting squiggly lines on paper as proving the existence of, entities that are impossible to see. (No one appreciates that more than Me.) What does surprise me is how much attention the whole thing got. I never thought I’d see the day when “CERN” trended on Twitter. It must have been extremely gratifying for the research team to see the name of their laboratory make the same prestigious list as #NorwayLovesBieber and #replace70ssongtitleswithpoop. To be honest I can’t remember the last time a physics breakthrough got this kind of international media attention. Kidding! Of course I do; I’m God. It was August 6, 1945, and it killed. But the larger point is: I’m still God. Your discovery doesn’t threaten Me. Unlike the CERN researchers I do not “sweat the small stuff”. I see the big picture, which is that no matter how much insight and control you gain over matter, you will never control time. You can’t see what’s coming; only I can. That’s why I win. Besides, even when it comes to the material world you haven’t even begun to scratch the surface of the absolutely crazy sh it I threw into quantum physics. For example, in about five years or so you’re going to smash together a quark and an antiquark and discover a new particle that actually folds out into a bed. It’s called a futon.
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HUMANITY'S understanding of the origin of the universe after the big bang has taken a historic leap forward with the discovery of a subatomic particle that scientists have been searching for and theorising about for almost 50 years. In jubilant scenes in Geneva and Melbourne, physicists learned that scientists working at the $10 billion Large Hadron Collider in Switzerland had found what they believe to be the Higgs boson or "God particle". The European Organisation for Nuclear Research, or CERN, announced the "milestone in the understanding of nature", saying it had found a new subatomic particle consistent with the Higgs boson. "The next step will be to determine the precise nature of the particle and its significance for our understanding of the universe," a CERN statement said. Peter Higgs, 83, the shy and softly spoken British physicist who, along with two other groups, published the conceptual groundwork for the particle in 1964, expressed his joy yesterday. He said he was "astounded at the amazing speed with which these results have emerged". "They are a testament to the expertise of the researchers and elaborate technologies in place," he said. "I never expected this to happen in my lifetime and shall ask my family to put some champagne in the fridge." In Melbourne, at the High Energy Physics Conference, where, along with Geneva, the results were announced, young physicists Anna Kropivnitskaya, Konstantin Toms and Maria Toms laughed and said the new particle, or boson, was science, not science fiction. "But it does improve our knowledge of the universe, the basis, the foundations," Konstantin Toms said. "It means the Standard Model of particle physics is true and complete and we have discovered the last missing piece." The discovery, by two separate teams, is hailed as virtual confirmation that the Standard Model of physics is correct, as the Higgs is a cornerstone of the model that describes the interactions of all known subatomic particles and forces. The Standard Model is a highly successful theory but has had several gaps, the biggest of which is why some particles have mass but some, such as the photon, do not. According to the Standard Model, the Higgs boson is the manifestation of the so-called Higgs field, an invisible energy field filling all space. The Higgs gives mass to other subatomic particles such as protons, neutrons, quarks and leptons. University of Melbourne particle physicist Geoff Taylor said it did this in a manner similar to the way water slowed down swimmers. "Subatomic particles feel the effect of the field like bodies moving through water. They gain mass, inertia," he said. The more a particle "feels" the field, the heaver it becomes. The boson is believed to exist in a treacly, invisible, ubiquitous field created by the big bang 13.7 billion years ago. The discovery was made by two separate teams, analysing data from the Large Hadron Collider, a giant underground lab where protons were smashed together at nearly the speed of light, yielding subatomic debris that was scrutinised for signs of the fleeting Higgs. Professor Taylor, who heads the Australian team participating in one of the two experiments - the A Toroidal LHC Apparatus or ATLAS - described the results as "fantastic" and confessed he'd put the champagne on ice in anticipation of the announcements. Like the second experiment - the Compact Muon Solenoid detector - ATLAS was designed to search for the Higgs, using the Large Hadron Collider built by CERN between 1998 and 2008. Two CERN labs, working independently of each other to avoid bias, found the new particle in the mass region of about 125-126 gigaelectronvolts, according to data they presented yesterday. Both said the results were "five sigma", meaning there was just a 0.00006 per cent chance that what the two laboratories found was a mathematical quirk. "The results are preliminary but the five sigma signal at around 125 GeV we're seeing is dramatic," said Joe Incandela, spokesman for one of the two experiments. In the 48 years since Emeritus Professor Higgs and five other scientists predicted the existence of the boson, wild claims have been made for the "God particle". Theoretical physicist Michio Kaku has said the discovery could begin to explain eternal questions sometimes called the mind of God: "To me, when we finally dicsover the 'God particle', this is just the beginning. This can open the floodgates for a whole new branch of theoretical physics. "There are eternal questions that cannot be answered in the framework of conventional physics. Is time travel possible, are there gateways to other universes . . . are there parallel universes?"
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Abwaan;845411 wrote: He is Kunciil Axmed Cali Cigaal...Don't worry about his obesity that seems not to bother him and the guy can sing yaan la is xaqirin.! if you say so. i normally listen to american band like maroon 5. have you heard of them.
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Abwaan;845408 wrote: lol.....Ugaas he is a legend's son who can really sing. With technology I believe he will be better than Egal; http://www.youtube.com/watch?v=kO-L7ZrDwVU&feature=share sxb. i don't listen to somali song that much and who is that fat guy ?
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