Originally posted by Xanthus: As for political, I was never beating the drums for the state, but whatever little good view I had of it is gone down the drain. I can picture Norf murmuring "Inantan yar yaa naga qabta, shiidh". I am sure he will be here shortly.

Originally posted by President Anwar: I would like to make clear to my fellow peace-loving countrymen, as my elder brother Bashir Goth believes, that I am not with the politics of aggression and hate. Is the author of the original article Bashir Goth's real brother? Similar views nonetheless.

Khat and dance as Israelis blot out intifada Nightlife in Tel Aviv on a par with the best in London and New York Conal Urquhart in Tel Aviv The Guardian It is Thursday night and the young of Tel Aviv are queuing for their supplies for the big night out of the Jewish week. At the city-centre kiosks, some customers ask for cigarettes or some gum, but about one in three furtively inquires: "Hagigat?" The shopkeeper looks straight ahead. His hand moves below the counter and he pulls out a small white capsule, which he exchanges discreetly for 50 shekels (£6.50). Hagigat is the latest in a line of legal drugs which add spice to Tel Aviv's already potent night life. It means "party" in Hebrew and is derived from khat, a plant chewed in Somalia and Yemen for its amphetamine effect. Other legal drugs include "liquid energy", a test tube of viscous plant extracts, and amyl nitrate or poppers. As Tuesday's suicide bomb attack in Beersheba demonstrated, the conflict continues; Palestinian frustration is boiling less than a 20-minute drive from Tel Aviv. Yet the party goes on, driven by a desire to escape the grim realities of Israeli life. In the past four years of the intifada, Tel Aviv's nightlife has gone from strength to strength. Larger and better bars, and clubs that would put London, New York and Paris to shame, open and close regularly to satisfy fickle tastes. The only major upset was the killing of 21 young people in June 2001 as they queued for the Dolphinarium nightclub on the city seafront. "It was only when there was the bombing at the Dolphinarium that it hit people," said Amir Bar Yitzhak, the editor of the Leyla nightlife website. "That was right at the centre of nightlife. That started a decline in people going out, but they got used to it. Then people decided they were going to go out in spite of everything and party until they fell down. That has levelled out a bit now and things are more normal." Legal drugs have become a major part of the hedonism. Hagigat is described on the packaging as "an aphrodisiac of organic material. 100% natural without chemicals". "Drink after food and take with a lot of water. Sell only to those over 18," it advises. Ronen Hazut, the owner of a city-centre kiosk, said: "Hagigat sells fast. People take this pill and say it's amazing. It's our biggest money maker and that's why we sell it." Moshe Haimkevitch, his partner who has taken the drug, said: "You feel high, but you're still alert and know what you're doing. You have power and energy, and most important, it makes you incredibly horny," he told the daily newspaper Yedioth Ahronoth. Another popular product is Liquid Energy, sold at a similar price. "This is drunk mainly during parties, and has to be shaken well. It has good effects and gives energy," said Mr Haimkevitch. In the past year several new venues have opened, described as "pick-up" bars. They feature large serving areas surrounded by scores of bar stools to ensure that everyone is visible to members of the opposite sex. David Tur opened Tel Aviv's largest bar, Lansky, last year. It cost more than a £1m to fit out and features 100 bar stools around the longest bar in the Middle East, if not Europe. "People come here because they want to see people. The customers here are mostly single or cheaters," he said. "This place is labelled a pick-up bar. I don't know what that means. There is a lot of interaction between people who don't know each other. If that makes it a pick-up bar, then it is." Mr Tur, who worked in London for several years, said the nightlife experience in Tel Aviv was totally different. "The interaction is very different here compared to London. Here you can see everybody, you are sitting next to everybody. It's not like you are going to a bar with your friends, you are sharing the experience with everyone," he said. Mr Bar Yitzhak added: "The atmosphere is warm, open and welcoming. Everything is straightforward. There is rarely any violence and you don't see any obvious drunkenness. You can always make friends; there is always someone to talk to." When drawn on the subject, most Tel Aviv residents favour compromise to achieve peace with the Palestinians. But on the whole they try to block out the military regime and the oppression of Palestinians. "I can appreciate it isn't much fun living in a refugee camp, or in the West Bank," Mr Bar Yitzhak said. "But I think it is hard for people elsewhere to imagine what it is like for someone to come to your favourite bar or cafe and blow themselves up. "We are in the middle of the barrel of a gun, yet everything is still so alive." A resident of Israel, originally from the UK, describes taking hagigat: I discreetly slip the capsule into my mouth and wash it down with Czech beer. Around the bar, I can see groups of men and women talking animatedly and some are dancing. Typical Brit, I won't dance or initiate conversation. "Where you are from?" pipes up one of my female neighbours."So you like Israel?" she continues. Rather than retreat into my shell, I smile broadly and start to chat. I feel a tingly sensation and a sense of confidence. I've had just one small glass of beer: this could only be the hagigat. The music is now flowing through my body. I look around the bar indulgently. This is a great night. Now I feel more than warm, almost sensuous.I need to stroke something, anything. The feeling remains with me for the next couple of hours. Eventually I feel a sense of anxiety and the warmth decreases. I feel impatient and I need another drink or maybe just another hagigat. http://www.guardian.co.uk/israel/Story/0,2763,1296958,00.html

Didn't understand why this was in the politics section. Moved it.

Originally posted by Abwaan: Ayaandarrada Soomaali haysata, wasiir warfaafin shakhsi sheeganaya oon xitaa Afsoomaali la fahmi karo qori karin amase aan dib u hubin wuxuu qoro! It is sad to see a "wasiir soomaliyeed" who can't even spell af-soomaali very well. The spelling is sad. The grammar is horrible. Too many mistakes in that "official" letter. Ilaahayoow adigaa ummaddaan u maqan.

Very interesting letter.

Ninkaan Cadde Ilaahay ummada haka qabto. Meel walba oo Puntland ka mid ah jufadiisuu xoogaa uga raadinayaa. Hadana ma dhuxul iyo in ummadda dhulkeeda la nabaad guuriyo ayuu ciidamo ugu diray carro Sanaag. Odaygaani innaba caadi ma aha.

Somalia had its first suicide bombing in Baidoa when there was no Ethiopian occupation and the ICU was on top of the world. This ideology is here to stay whether we like it or not. It has arrived and we have to live with it. Will Somalis tolerate such act in the long run? Probably! ... but this phenomenon also has the potential of triggering a tribal conflict of immense proportions.

Originally posted by Allamagan: Maaweeladu si fiican ayeey usocotaa.. lool. Shimbirayahow heesa dheh. Innaba caadi ma aho sheekada Meles.

^ .

http://www.biyokulule.com/Cape%20of%20Less%20Hope.htm

Bombarded by the Italian attack ships. Bombarded by the Americans gun ships and warplanes. The former capital city of the Osmania Kingdom. Stunning mountainous region on the Indian Ocean Declared "not part of Puntland" by city spokesman during the ICU/TFG war. An Islamic Court was declared. Full of date farmlands and Frankincense trees inherited from generation to generation.

I agree with Juje. I don't think the ICU should start killing these "gudoomiyaal degmo". Not a good military strategy. For one, these "gudoomiyeyaal" are almost certainly considered "important leaders" by their sub-clans and since Somalis are a mixture of sub-clans, such decapitation would only fuel more anger on the part of "reer hebel" to work with the TFG and defy "the murderers who killed their leader". That is just how things are back home. Popular support = clan is happy.

^

Chemical & Engineering News Luminous With Promise Visible even from space, the conspicuous chemistry of bioluminescence continues to open new research and technology niches Ivan Amato Almost 12 years ago, the British merchant vessel S.S. Lima was cruising under a clear night sky along a southwesterly course in the Indian Ocean about 150 miles off the coast of Somalia. "A whitish glow was observed on the horizon," a crew member later reported. "After 15 minutes of steaming, the ship was completely surrounded by a sea of milky white color with a fairly uniform luminescence. ... It appeared as though the ship was sailing over a field of snow or gliding over clouds." Overhead, in the dark silence of space, a U.S. Department of Defense meteorological mapping satellite was zooming by, looking down with an uncommonly sensitive light detector. A decade later, with the "milky sea" report from the Lima as the clue, bioluminescence researchers retrieved the satellite's archived imagery. In images captured on Jan. 25-27, 1995, Steven H. D. Haddock of the Monterey Bay Aquarium Research Institute, Steven D. Miller of the Naval Research Laboratory, and their colleagues could make out a Connecticut-sized patch of slightly bright pixels right where the Lima had been cruising. Using image enhancement techniques, the scientists discerned a living phenomenon that no one had seen from space before. In their write-up of the findings, the scientists proudly stated that they had bagged "the first satellite measurements of bioluminescence from a milky sea" (Proc. Natl. Acad. Sci. USA 2005, 102, 14181). Generated most likely by the bacterium Vibrio harveyi, this awesome display of flamboyant biological chemistry happened on a vast scale: The researchers estimate that it took a bloom of 40 billion trillion (4 X 1022) bioluminescent cells to generate the milky sea that the Lima had encountered. This October at the 14th International Conference on Bioluminescence & Chemiluminescence in San Diego, Haddock's recounting of this brilliant moment in the annals of microbial chemistry was all the more striking in terms of scale. Other scientists at the meeting detailed how angstrom-scale displacements of specific amino acids influence the function of the luciferase enzymes that perpetrate much of the world's bioluminescence, including that of V. harveyi. Bioluminescence, it appears, is a phenomenon that spans 14 orders of spatial magnitude. The collective message from the 100 or so researchers at the conference was that luminescent chemistry, whose expressions in the biological world span from fungi and fireflies to plankton and jellyfish, continues to diffuse into and energize some of the hottest research arenas. Gene expression analysis, pathogen detection, and high-throughput screening and assays for pharmaceutical research are just some of these areas. Evidence for the diffusion of bioluminescence shines everywhere in the molecular, cellular, and biomedical sciences. "If you look at any journal today, you will see all of these beautiful, colorful images," observed Aladar A. Szalay, president of the International Society for Bioluminescence & Chemiluminescence (ISBC) and chairman of the San Diego symposium. "All of it is coming as a result of this research community," claimed Szalay, who is also president and chief executive officer of Redland, Calif.-based Genelux, a company that is developing bioluminescence-based agents and tools for biomedical applications. "These are examples of how basic science turns into things you would never expect," said Keith Wood, a longtime bioluminescence researcher at Madison, Wis.-based Promega. Luminescent chemistry derived from fireflies, click beetles, and sea pansies accounts for a significant portion of the $175 million in revenues his company earned in 2006 from the sales of analytic and diagnostic kits, Wood said. Participants convened at the San Diego conference from 17 countries to share a passion, in this case a passion for understanding, exploiting, and even just playing with luminescent chemistry. Patrick Hickey, for example, came armed with vials of luminescent powders, and he was as ready to turn a glass of water into a crowd-pleasing glowing liquid as to expound upon encounters with luminescent mushrooms. Hickey is the founder and director of LUX Biotechnology in Edinburgh, Scotland, a small company that sells calibration standards, light detectors, and other laboratory accoutrements useful to his fellow luminescence aficionados. He has a knack for fanning interest in the field, and he recently partnered with a theater troupe in Glasgow to create bioluminescent stage props as well as images and movies of bioluminescent creatures for a "staged cantata" called "The Paper Nautilus," which ran three performances in early November. The goal of the collaboration, according to a promotional flyer, was to "transfer 'living light' from the laboratory to the stage, producing a magical biochemical display." To be sure, bioluminescence has a way of prodding those who witness and study it to come up with wild ideas. Perhaps that's because of its inherent outlandishness: Consider, for instance, those flying beetles that light up summer evenings with built-in blinking lights made of biological tissue. And then consider that this same sort of chemistry is finding its way into potential medical innovations. The biggest buzz at the meeting came from the work of biomedical researchers, who described how bacteria and viruses engineered to glow are cranking up momentum in an emerging field called oncolytics. Building luminescent properties into oncolytic—cancer-busting—infective agents has been opening up surprising new approaches to tracking and treating cancer, even the small, distributed, and hard-to-detect specks of diseased tissue that so often are the ones that ultimately kill. "This is one of the most exciting things I have heard," commented Bruce Branchini, a chemist at Connecticut College, New London, and president-elect of ISBC. As the word implies, chemiluminescence is the phenomenon by which a chemical vents some energy by emitting light. Bioluminescence is a version of chemiluminescence that takes place in living organisms. Most bioluminescence depends on enzymes known as luciferases. Luciferases catalyze the oxidation of small-molecule substrates known as luciferins in the presence of one or more cofactors, among them oxygen, adenosine triphosphate, and metal ions. A product of this reaction is light, exemplified by the green glow from a firefly's lantern. Unlike the chemically generated light of bioluminescence, the light generated by fluorescent proteins—for example, green fluorescent protein (GFP), which is used extensively in cellular and biomolecular studies—is the result of excitation from another light source. Produced by certain jellyfish, GFP fluorescence is stimulated by bluish light from a separate but nearby bioluminescent reaction. The earliest written records of bioluminescence date as far back as 2,500 years, but scientists continue to uncover new details about the phenomenon. Consider Kazuki Niwa of the National Institute of Advanced Industrial Science & Technology, Osaka, Japan, who investigated a mystery in the firefly's biosynthesis of luciferin. In bench studies, Niwa found that only the D-isomer of synthetic firefly luciferin could be made to bioluminesce. Scientists have long thought that the firefly makes only the L-isomer because its precursor, the amino acid cysteine, is available only in the L-form. Niwa discovered a potential way out of this enantiomeric paradox by showing that a firefly's luciferase enzyme, in addition to its role in eking light out of luciferin, can also convert L-luciferin into D-luciferin, the apparent bioluminescent enantiomer. Conference organizer Szalay, who sat in the front row for every talk and nervously oversaw the meeting like it was his own wedding, is a champion of the role that basic studies like Niwa's play in the development of light-emitting technologies that can transform lives and societies. He and his colleagues at Genelux are convinced they are pursuing a cancer diagnosis and treatment lead that has this kind of potential. Genelux' Tony Yu, for example, described how he and coworkers used bacteria, into which they had inserted a light-generating luciferase gene, to help visualize tumors and even small metastatic offshoots of primary tumors in live mice. After intravenously injecting the bacteria, the researchers tracked the distribution of the microbes in anesthetized mice placed in a chamber fitted with a low-light camera capable of picking up luminescent signals through the animal's intact skin. In imagery taken over a period of days, the signals first are visible throughout the animal before localizing in the liver and then disappearing as the animal's immune system clears the microbe. The researchers repeated the experiment in nude mice deliberately made ill with a leg-based glioma tumor. Over a period of days, Yu said, "the bacteria clear from the blood and concentrate in the tumor." This finding gels with previous data indicating that tumors serve as "immunological safe havens" for some bacteria and viruses. The researchers have seen similar results with a variety of glowing bacteria in several cancer models, including ones for breast, lung, and bladder cancer. "The bacteria even find metastatic tissue," which has spread from the original tumor and often is too small or otherwise unapparent for surgeons to find during operations, Yu noted. Yanghee Woo of Memorial Sloan-Kettering Cancer Center, in New York City, reported that she and her coworkers, including lab director Yuman Fong, have been testing a fluorescent version of the herpes simplex virus (HSV-1) for its value in detecting and shrinking tumors. Recently, researchers have been finding that HSV-1 selectively replicates in a number of different cancers, including lung, esophageal, gastric, pancreatic, and colorectal cancers. "We were struck by just how specific the oncolytic virus is for cancer," Woo said during a presentation that portrayed the potential medical versatility of the fluorescently labeled HSV-1 virus designated NV1066. The virally infected cells and tissues glow green when bathed by a beam of light. A primary goal of Woo's group is to develop new tools for cancer surgeons. The idea is to inject patients with a fluorescent agent like NV1066 that would enable the surgeons to literally see virally infected and therefore presumably cancerous cells and tissues. "What is exciting is that the viruses showed small areas of cancer that we couldn't see otherwise," Woo said, referring in this case to small crumb-sized nodules of cancerous stomach tissue in a mouse model her team was studying. Such reagents could eventually enable surgeons, perhaps using minimally invasive, camera-equipped laparoscopes and endoscopes, to know with more precision what tissue they need to excise. In an extensive investigation of the technique's potential utility, a Sloan-Kettering team led by Fong reported earlier this year that a single dose of NV1066, administered either locally or systemically, zeroes in on "110 types of cancer in 16 different primary organs" (FASEB J. 2006, 20, 726). For Christopher Contag of Stanford University, the ability to render recombinant vaccinia virus visible with a luciferase gene has helped him push forward a cancer-attacking strategy that he and colleagues have been pursuing for years. In their tack, they begin with so-called cytokine-induced killer (CIK) cells, a type of immune cell known to home in on tumors and to sometimes put a drag on the cancer's growth. Contag's group preloads the CIKs with the luciferase-expressing vaccinia virus particles, which the CIKs then smuggle directly into tumor tissue. In experiments reported earlier this year in Science (2006, 311, 1780) and recounted by Contag at the meeting, the researchers gave an intravenous dose of these virus-infected CIK cells to mice with tumors. They found that a single dose of this oncolytic preparation cleared the disease from up to 75% of the mice. Other scientists are heartened by this result but caution that efforts to translate the technology to people have only just begun. A key concern is whether the initial treatment primes the immune system to take on and neutralize the virus in second and subsequent treatments. Contag has shown, however, that virus cloaked within CIK cells appears not to elicit the immune system's ire. This opens the possibility for effective delivery, even to solid tumors, which has not been demonstrated before with this virus, Contag said. "Imaging enables the in vivo study of cell biology and can reveal the nuances of disease mechanism," Contag said, referring to the use of both fluorescent and bioluminescent tags. If all goes well with the CIK-cloaked oncolytic virus technique, he added, "it may become possible to eliminate the last tumor cell in cancer patients and prevent relapses." Toward that end, Contag and several partners founded Xenogen, a company that was recently acquired by Caliper Life Sciences, to commercialize luminescence-based tools for studying biological processes in vivo and accelerating drug development. Curing cancer. That would be quite a windfall from what started as mere curiosity about the luminosity of blinking fireflies and jellyfish. http://pubs.acs.org/cen/science/84/8449sci2.html

Calculations Calculating potential bacterial population Under the assumption that bacteria were indeed responsible for milky seas, we estimated the minimum population that would be detectable by the OLS sensor. Lab cultures of bioluminescent bacteria with emission properties that are similar to commonly-found free-living species were grown. Their spectrum and per-cell photon emission were recorded. Given the OLS minimum detectable power per unit area (adjusted to account for atmospheric attenuation and partial overlap between the OLS response and the bacterial spectra), the total equivalent bacteria per unit area was computed. This allowed for extrapolation to the total population based on the glowing surface area that was observed by the satellite. Our conservative estimate of 4×1022 cells participating in this event is roughly the same as the estimated total background free-living bacteria present in the upper 200m of all the oceans of the world.7 Satellite remote sensing has provided our first objective view of the scale, structure, and—in some respects—integrity of a maritime legend. Indeed, the space perspective has enabled an ‘infusoria’ population estimate dismissed as impossible by the knowledgeable Professor Aronnax, protagonist of the Jules Verne's classic novel 20,000 Leagues Under the Sea. 8 More importantly, this capability instills hope within a research community hindered by the elusive nature of milky seas. Information available from the satellite observations is inherently limited so additional details on milky seas must await in situ observations by research vessels properly equipped for depth-resolved chemistry, organics, and radiometry. The next step in our research is to follow several new leads that have emerged since the announcement of our findings. Our focus will then shift towards the National Polar-orbiting Operational Environmental Satellite System (NPOESS), which is due to come into operation in around 2010. This system is scheduled to carry low-light sensors, which are currently being examined to determine their potential for bioluminescence detection. These could hold promise for future observations of milky seas and possibly the first satellite-directed ship excursions into the surreal. http://spie.org/x8854.xml?highlight=x2420

Satellite images confirm mystery glow in ocean ‘Milky sea’ may be caused by colony of bioluminescent bacteria Mariners have long told of rare nighttime events in which the ocean glows intensely as far as the eye can see in all directions. Fictionally, such a "milky sea" is encountered by the Nautilus in Jules Verne classic "20,000 Leagues Under the Sea." Scientists don't have a good handle what's going on. But satellite sensors have now provided the first pictures of a milky sea and given new hope to learning more about the elusive events. The newly released images show a vast region of the Indian Ocean, about the size of Connecticut, glowing three nights in a row. The luminescence was also spotted from a ship in the area. "The circumstances under which milky seas form is almost entirely unknown," says Steven Miller, a Naval Research Laboratory scientist who led the space-based discovery. "Even the source for the light emission is under debate." The leading idea Scientists suspect bioluminescent bacteria are behind the phenomenon. Such creatures produce a continuous glow, in contrast to the brief, bright flashes of light produced by "dinoflagellate" bioluminescent organisms that are seen more commonly lighting up ship wakes and breaking waves. "The problem with the bacteria hypothesis is that an extremely high concentration of bacteria must exist before they begin to produce light," Miller told LiveScience. "But what could possibly support the occurrence of such a large population?" One idea, put forward by the lone research vessel to ever encounter a milky sea, is that the bacteria are not free-living, but instead are living off some local supporting "substrate." "This previous excursion reported the presence of bioluminescent bacteria, which were found to be living in association with an algal bloom," Miller explained. "So, our best working hypothesis is that we are witnessing bioluminescence produced by bacteria that are colonizing some kind of organic material present in the water," he said. "Satellite detection will hopefully allow us to target milky seas with properly equipped research vessels that will then be able to answer all these questions definitively." The mysterious seas The event occurred in 1995 and was finally analyzed and reported last week in the Proceedings of the National Academy of Sciences. The mystery highlights how little scientists know about the ocean. Milky seas appear to be most prevalent in the Indian Ocean, where there are many trade routes, and near Indonesia. "But there could be other areas we simply don't know about yet," Miller said. "In fact, we're already beginning to receive feedback from additional witnesses of milky seas. Some of these accounts occurred in regions we had not thought to look before, and we're currently working to find matches with the satellite data."

Originally posted by Nayruus: During the visit, he was closely guarded and never had been given chance to get out of the sight of the escorting team. Very troubling news indeed. I always knew my favourite Somaliland politician is being followed by the "gang". Siilaanyo however, is plotting and plotting. He will set himself free and lead the Somali nation. Thanks Nayruus for the excellent report. Free Siilaanyo!

The Syrian President that is.